What is the recommended treatment choice for a woman with an uncomplicated urinary tract infection?

The recommended treatment choice for a woman with an uncomplicated urinary tract infection (UTI) is to use a fluoroquinolone or nitrofurantoin for a duration of 3-5 days. This approach aligns with clinical guidelines that suggest shorter courses of antibiotics can be effective for uncomplicated cases, thus minimizing potential side effects and antibiotic resistance.

Fluoroquinolones, such as ciprofloxacin, and nitrofurantoin are both appropriate options because they demonstrate good efficacy against the most common pathogens responsible for uncomplicated UTIs, including Escherichia coli. The shorter treatment duration of 3-5 days tends to be just as effective as longer courses, particularly in uncomplicated cases, while also reducing unnecessary exposure to antibiotics.

In contrast, while other longer or less targeted regimens might be effective, they do not align with the current focus on using the least intensive treatment that will still provide effective care. Ultimately, the use of a shorter duration and targeted therapy helps to optimize patient outcomes while also considering the larger issue of antibiotic stewardship.