What is the major risk associated with PPROM and PROM?

The major risk associated with preterm premature rupture of membranes (PPROM) and premature rupture of membranes (PROM) is infection. When the amniotic membranes rupture, the protective barrier that helps keep the uterus sterile is compromised, increasing the risk of ascending infections from the vaginal canal into the uterus. The most significant concern is the development of chorioamnionitis, which is an infection of the amniotic fluid and membranes. This condition can have serious implications for both the mother and the fetus, including sepsis, preterm labor, and complications that may require an emergency delivery.

The presence of infection due to PPROM or PROM is a critical factor that healthcare providers monitor closely. Management often includes assessing for signs of infection and potentially administering antibiotics to protect the mother and fetus, especially if labor is imminent or there are other concerning clinical signs.